Unfortunately, like the city-builders that have come before, Skylines does not have a mixed-use zone. The residential and commercial zones have a low-density and a high-density variant. In addition to the traditional SimCity set of residential, commercial, and industrial zones, Skylines has added an office zone to the mix, which allows you to provide jobs for educated workers. Like other city-builders, Skylines includes zones. The game has zones for residential, commercial (retail), industrial, and office.